Recurrent spontaneous abortion is a health hassle with causes. Apoptosis should have a primary function in the system. The purpose of this look at was to locate Bcl-2, (P53) as an antiapoptotic, proapoptotic proteins in the trophoblastic tissues in cases with recurrent being pregnant loss. Immunohistochemistry analysis of (P53), Bcl-2 proteins the use of paraffin embedded sections of placental tissues obtained from 108 cases divided into 3 agencies: 66 Toxoplasma gondii high quality cases with recurrent abortion,22 Toxoplasma gondii terrible cases with recurrent abortion, 20 cases without a history of abortion as a manipulate group. The suggest value of the expression of (P53) protein changed into (35.3±5.738), which is considerably better than that of the second group (19.88±3.433), the third institution (12.3±5.635). The excessive expression for (P53) protein in instances with recurrent abortion may play a role inside the acceleration of placental apoptosis which results in recurrent spontaneous abortion.