Aim

To determine the relation between first trimester maternal BMI, HbA1c and GDM with fetal and maternal outcome including complications

Objectives

1.       To determine the relation between 1_st trimester maternal BMI and gestational diabetes mellitus

2.       To estimate the HbA1C levels in order to rule out overt diabetes in antenatal mothers.

3.       To describe the fetal and maternal outcome among GDM patients

4.       To determine fetal and maternal outcome with respect to first trimester maternal BMI

Material & Methods

Study Area

The study was conducted among patients attending Department of Obstetrics and Gynecology of Mallareddy Medical College for Women

Study Design: Prospective Observational study

Study Period: September 2022 to February 2024

Study Population: Pregnant women attending Outpatient department and delivering at Mallareddy Medical College for Women hospital, Hyderabad

Method: After taking consent based on inclusion and exclusion criteria, total of about 126 singleton pregnant women presenting at our antenatal clinic were

enrolled in this prospective study.Demographic and Obstetric data of pregnant women were noted at their first antenatal visit.General and obstetric examination was done.Pregnant women were informed and counselled regarding Obstetric history taking and general examination.General examination of pregnant women in first trimester was performed,weight of the patient in kgs and height of the patient in centimetres were recorded their BMI calculated and recorded.Blood sample were collected for HbA1c level measurement.Oral glucose tolerance test (OGTT) was performed with 75 grams of glucose between 24-28 weeks of gestation after 8 hours of fasting, any medication like steroids, Beta blockers were stopped 48 hours before the test.Weight of the patient at the time of delivery was noted in GDM mothers to

assess maternal weight gain during pregnancy. Blood glucose levels in GDM mothers after delivery, complications if any during or after delivery of the baby were recorded.

Post delivery APGAR score, blood glucose levels, birth weight of the baby, maturity of the baby were recorded.