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VOL. 3, ISSUE 2 (2021)
Ferric carboxymaltose-A novel formulation of iron in treatment of postpartum iron deficiency anaemia
Authors
Aprajita Kumari, Geeta Sinha, Farhat Mazhari
Abstract
Aims and Objectives: Compare the efficacy and safety of FCM with oral iron in improvement of haematological parameter and iron store in post partum iron deficient women. Methods: Postpartum women were screened for IDA. 70 women in each group were randomized. One group received FCM as per calculated dose with folic acid and other 70 women received oral ferrous sulphate 200 mg TDS + folic acid. Both groups were followed up for 6 wks. Any adverse effects were noted. Hb level, Red cell indices & Iron stores were monitored. Results: At 6 wk, Mean Hb rise 3.3+/- 0.8 in FCM group, Where as 2.2+/- 1.0 in oral group(P=0.00, Highly significant), MCV increases by 13.0+/-8.1 in FCM group(77 to 90 fl) where as 4.5+/-6.9 in oral group, P=0.00. TIBC decreases by 416 mcg/dl to 325 mcg/dl in FCM group. Whereas 422 to 388 mcg/dl in oral group (P=0.00), Sr ferritin rises by 138.1+/-30.8 ng/ml in FCM group. Whereas 2.2+/- 1.8 in oral group (P=0.00). Conclusions: FCM is more efficacious than oral iron in improving haematological parameters and restoring iron stores with comparable side effects, convenient dosing schedule and no need of test dose
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Pages:14-15
How to cite this article:
Aprajita Kumari, Geeta Sinha, Farhat Mazhari "Ferric carboxymaltose-A novel formulation of iron in treatment of postpartum iron deficiency anaemia ". International Journal of Gynaecology and Obstetrics Research, Vol 3, Issue 2, 2021, Pages 14-15
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