Non immune hydrops fetalis may be associated with multiple fetal anatomic and functional abnormalities including cardiac structural defects and rhythm abnormalities which cause pressure and volume overload of right side of fetal heart and eventually venous hypertension and systemic edema. Fetal panvalvular calcification with Coarctation of aorta is an unusual and rare ultrasound finding associated with defunctioning myocardium leading to Non-immune hydrops fetalis (NIHF).We are reporting a case of 32 year old G3P2L2 reported at 23 weeks period of gestation from primary health centre with ultrasound examination report suggestive of all panvalvular cardiac calcifications. Fetal echo was performed and provisional diagnosis of interrupted aortic arch, panvalvular calcification with biventricular hypertrophy and moderate pericardial effusion was made. Patient was evaluated for non immune hydrops fetalis and cordocentesis was performed at 27 weeks and karyotype of lymphocyte culture with GTG revealed 47, XX, +21. On serial imaging fetal hydrops ensued followed by intrauterine fetal death. Subsequent reports confirmed all valve calcification with coarctation of aorta in fetus with Down syndrome.