Endometriosis (E) is a chronic, benign, estrogen-dependent inflammatory disease affecting approximately 10% of reproductive age women and 35–50% of women with infertility and pelvic pain (PP). It is defined as the presence of endometrial like tissue (glands and stroma) outside the uterus, which induces a chronic inflammatory reaction, scar tissue, and adhesions that may distort a woman’s anatomy of the pelvis. Association between (E) and (CPP) is suggested by the observation that among women who undergo laparoscopy, (E) is found in 1/3 who undergo surgery for (CPP). This is an evidence based narrative review conducted by searching Medline up to (2017) and other online articles from PubMed, by using terms like (E), quality of life, Chronic pelvic pain, pain scales and psychology. This reviw concluded that Experiencing endometriosis symptoms is associated with lower health-related quality of life (HRQL). Importantly, as symptom severity and number of symptoms increase, HRQL further deteriorates